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Image Search Results
Journal: International Journal of Retina and Vitreous
Article Title: Safety and tolerability evaluation after repeated intravitreal injections of a humanized anti-VEGF-A monoclonal antibody (PRO-169) versus ranibizumab in New Zealand white rabbits
doi: 10.1186/s40942-020-00235-y
Figure Lengend Snippet: ERG analysis of NZW rabbits as a function of time after intravitreal injections. a The effects of the intravitreal PRO-169 (white bars) and ranibizumab (dark bars) on the dark-adapted ERG responses after 30 days of each injection. The dark-adapted retinal response is represented by the mean ± SEM V Max ratio of the ERG (b-wave). b Time dependent effects of repeated injections of PRO-169 and ranibizumab on retinal function of rabbits. The difference of the log semi saturation constant (experimental-control) is represented by the mean ± SEM. V Max ratios are around 1 and log σ differences are around 0, indicating no damage to the road system
Article Snippet:
Techniques: Injection
Journal: International Journal of Retina and Vitreous
Article Title: Safety and tolerability evaluation after repeated intravitreal injections of a humanized anti-VEGF-A monoclonal antibody (PRO-169) versus ranibizumab in New Zealand white rabbits
doi: 10.1186/s40942-020-00235-y
Figure Lengend Snippet: Histologic examination of the central retina for PRO-169 ( a ) vs ranibizumab ( b ) after the 1st Ivt injection (D32), for PRO-169 ( c ) vs ranibizumab ( d ) after the 2nd Ivt injection (D63), and for PRO-169 ( e ) vs ranibizumab ( f ) after the 3rd Ivt injection (D94). No retinal toxicity was found in any eyes (x40)
Article Snippet:
Techniques: Injection